The final packed-out show was held in a black room with the designer's name up in lights and an amber runway.
The feminine collection of mostly dresses was created in a range of vibrant reds, pinks, yellows, purples and greens.
The garments featured rich tapestry-like patterns and textured fabric.
Models wore bright coloured eye make-up and flipped back hair adorned with flowers, feathers and berries.
Designer Akira Isogawa said it was important to him that hair and make-up complement his designs.
"It's vital to complete the look," he said.
"It's not just about the clothing but the styling as well - the shoes, the skin, the colour and the hair."
Music by Icelandic group Sigur Ros added to the other-worldly feel, as models glided down the catwalk on 10cm wedge shoes.
It was a triumphant return for Akira, who was absent from the event last year.
"We didn't participate in Australian Fashion Week last year, so I feel a bit nervous," the designer admitted before the show.
He needn't have worried, receiving rapturous applause as the show closed.

Phil Oh’s Best Street Style Photos From the New York Fashion Week Spring 2023 Shows
This season New York Fashion Week has brought in a worldwide crowd of stars thanks to a packed season that even includes shows...